There are 8 pentominoes and 8 hexominoes that fit in a 3×3 cell. The combined set seems to cry out to be presented in a 4×4 grid of 3×3 blocks, with the pentominoes and hexominoes in checkered positions:

The best I could think to do was make a figure that is connected, hole-free, and has a rotationally symmetrical pattern of connections between blocks. I had hoped to make them into a geomagic square, but now I’m pessimistic about that working. And the trick from my magic 45-ominoes of making all rows and columns have the same number of cells in polyominoes won’t work here because the total number in each row of 3×3 blocks is 22, which isn’t divisible by 3.

I’ve looked before at problems involving moving a single cell at a time to cycle through a set of polyforms. Because this set has equal numbers of pieces at two consecutive sizes, it invites using adding and removing single cells, rather than moving them, as the action for taking one piece to the next in a path:

Because the X pentomino has only one possible predecessor or successor, it cannot be part of a cycle, but it is still possible to make a path through all of these pentominoes and hexominoes with the X as one of its endpoints.